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Abstract #1688

Tabletop magnetic resonance elastography for the measurement of viscoelastic properties in soft tissue micro samples

Selcan Ipek-Ugay 1 , Michael Ledwig 2 , Toni Driele 2 , Jing Guo 3 , Ingolf Sack 3 , and Jrgen Braun 4

1 Radiology, Charit-Universittsmedizin Berlin, Berlin, Berlin, Germany, 2 Pure Devices GmbH, Wrzburg, Germany, 3 Radiology, Charit-Universittsmedizin Berlin, Berlin, Germany, 4 Medical Informatics, Charit-Universittsmedizin Berlin, Berlin, Germany

A tabletop magnetic resonance elastography (MRE) system was developed based on a 0.5T permanent magnet for the analysis of viscoelastic properties of tissue samples. The system allowed us the measurement of viscoelastic parameters in soft tissue samples in a frequency range of 500-1000 Hz. The data are in good agreement to published data acquired in a 7T-highfield superconducting magnet. Acquiring the same viscoelasticity information by low costs with little requirements for space and maintenance might support MRE developments towards mechanics based histopathology capable to links viscoelastic constants with the etiology and pathogenesis of diseases.

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