Abstract #1696
Magnetic Resonance Elastography of cysts and fluid filled cavities
Jing Guo 1 , Sebastian Hirsch 1 , Sebastian Papazoglou 1 , Kaspar-Josche Streitberger 1 , Andreas Fehlner 1 , Juergen Braun 2 , and Ingolf Sack 1
1
Department of Radiology, Charite -
Universitaetsmedizin Berlin, Berlin, Berlin, Germany,
2
Department
of Medical Informatics, Charite - Universitaetsmedizin
Berlin, Berlin, Germany
MRE can differentiate small lesions based on their
stiffness or softness compared to surrounding healthy
tissue. However, in tissue with fluid filled cavities
the obtained elastograms are biased due to effects of
the lesion's geometry to the refracted wave field,
resulting an overestimation of stiffness values. We
analyze this effect by numerical simulations and MRE
data of phantoms and in vivo cysts in the abdomen and
brain. Our results indicate severe overestimation of
viscoelasticity in cysts unlike other fluid filled parts
of the tissue. We show that this effect is a result of
resonances in oscillating cavities with regular
interfaces.
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