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Abstract #1696

Magnetic Resonance Elastography of cysts and fluid filled cavities

Jing Guo 1 , Sebastian Hirsch 1 , Sebastian Papazoglou 1 , Kaspar-Josche Streitberger 1 , Andreas Fehlner 1 , Juergen Braun 2 , and Ingolf Sack 1

1 Department of Radiology, Charite - Universitaetsmedizin Berlin, Berlin, Berlin, Germany, 2 Department of Medical Informatics, Charite - Universitaetsmedizin Berlin, Berlin, Germany

MRE can differentiate small lesions based on their stiffness or softness compared to surrounding healthy tissue. However, in tissue with fluid filled cavities the obtained elastograms are biased due to effects of the lesion's geometry to the refracted wave field, resulting an overestimation of stiffness values. We analyze this effect by numerical simulations and MRE data of phantoms and in vivo cysts in the abdomen and brain. Our results indicate severe overestimation of viscoelasticity in cysts unlike other fluid filled parts of the tissue. We show that this effect is a result of resonances in oscillating cavities with regular interfaces.

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