Abstract #1709
High resolution three dimensional morphometry and nasal air flow of the mammalian nose from multi-modal imaging
Thomas Neuberger 1,2 , Joseph P Richter 3 , Christopher R Rumple 3 , Andrew P Quigley 3 , Allison N Ranslow 3 , Timothy M Ryan 4 , Timothy D Stecko 4 , Benison Pang 5 , Blaire Van Valkenburgh 5 , and Brent A Craven 3
1
Huck Institutes of the Life Sciences,
Pennsylvania State University, University Park, PA,
United States,
2
Department
of Biomedical Engineering, Pennsylvania State
University, University Park, PA, United States,
3
Applied
Research Laboratory, Pennsylvania State University,
University Park, PA, United States,
4
Center
for Quantitative X-Ray Imaging, Pennsylvania State
University, University Park, PA, United States,
5
Department
of Ecology and Evolutionary Biology, University of
California, Los Angeles, CA, United States
This paper presents the current state-of-the-art
techniques for reconstructing nasal form and function.
The mammalian nasal cavity is a multi-purpose organ that
houses a complex arrangement of bony turbinals and a
tortuous, interconnected airway in which respiratory air
conditioning, filtering of environmental contaminants,
and chemical sensing occur. This study combines MRI and
CT to build high resolution three dimensional models of
the nasal cavity of six different mammals. The
reconstructed models were used in computational fluid
dynamics (CFD) simulations of nasal airflow. Future CFD
simulations may include respiratory heat and moisture
exchange and odorant mass transport.
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