Abstract #1716
Singleshell diffusion MRI NODDI with in vivo cervical cord data
Francesco Grussu 1 , Torben Schneider 1 , Hui Zhang 2 , Daniel C. Alexander 2 , and Claudia A. M. Wheeler-Kingshott 1
1
NMR Research Unit, Department of
Neuroinflammation, Queen Square MS Centre, UCL Institute
of Neurology, London, England, United Kingdom,
2
Department
of Computer Science and Centre for Medical Image
Computing, University College London, London, England,
United Kingdom
Neurite Orientation Dispersion and Density Imaging (NODDI)
is a novel diffusion MRI technique which relies on
doubleshell acquisition. To date, it is not clear
whether a reduced NODDI model could be fitted to
singleshell diffusion data of areas such as the spinal
cord. In this work, we compare singleshell estimates of
NODDI parameters to doubleshell ground truth in the
healthy cervical cord in vivo, and our results would be
informative for retrospective NODDI analysis of in vivo
singleshell diffusion data of the same area.
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