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Abstract #1722

White Matter and Grey Matter Magnetisation Transfer Measurements in the Lumbo-Sacral Enlargement: A Pilot Study With the Use of Radial Acquisition Profile at 3T

Marios C. Yiannakas 1 , Rebecca S. Samson 1 , Chinyere O. Ugorji 1 , David H. Miller 1 , and Claudia A. M. Wheeler-Kingshott 1

1 Neuroinflammation, UCL - Institute of Neurology, London, London, United Kingdom

In this work the possibility of obtaining magnetisation transfer ratio (MTR) measurements in grey matter (GM) and white matter (WM) within the lumbo-sacral enlargement (LSE) is investigated. This is achieved with the use of radial acquisition profile to alleviate the effects of physiological motion associated with this level of the spinal cord. The method presented maybe used with a commercially available MRI system and future studies will be directed at assessing the value of this method to study neurological disease affecting the lumbar spinal cord.

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