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Abstract #1738

Early high b-value diffusion MRI of the preterm infant brain highlights radial organisation of the developing cortex

Kerstin Pannek 1 , Joanne George 1 , Paul Colditz 1 , Roslyn Boyd 1 , and Stephen Rose 2

1 The University of Queensland, Brisbane, Queensland, Australia, 2 The Australian E-Health Research Centre, CSIRO, Brisbane, Queensland, Australia

Diffusion MRI is a promising tool for assessing brain maturation in preterm infants. In preterm infants scanned between 30 to 33 weeks postmenstrual age, we investigated the impact of the diffusion acquisition scheme on the resulting diffusion measures. A higher b-value led to increases in diffusion anisotropy in cortical grey matter, while anisotropy remained largely unchanged in white matter. High b-value diffusion MRI may provide unique insights into cortical development in prematurely born infants.

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