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Abstract #1762

Radiological evaluation of quiet T1-weighted PETRA in comparison with routine brain MPRAGE in pediatric patients

Noriko Aida 1 , Kumiko Nozawa 1 , Yuta Fujii 1 , Koichiro Nomura 1 , Tetsu Niwa 1 , Masahiko Sato 2 , Koki Kusagiri 2 , Yasutake Muramoto 2 , Yuichi Suzuki 2 , Katsutoshi Murata 3 , Matthew Nielsen 3 , David Grodzki 4 , and Takayuki Obata 5

1 Radiology, Kanagawa Children's Medical Center, Yokohama, Kanagawa, Japan, 2 Radiological technology, Kanagawa Children's Medical Center, Yokohama, Kanagawa, Japan, 3 Research & Collaboration, Imaging &Therapy System, Siemens Japan, Tokyo, Japan, 4 Magnetic Resonace, Siemens Healthcare, Erlangen, Bavaria, Germany, 5 Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan

Clinical efficacy of a prototype T1-weighted PETRA was prospectively evaluated compared to MPRAGE in 56 sedated pediatric patients.@PETRA requires very limited gradient activity and allows for inaudible scanning. Only 4.8 dB(A) higher than the background acoustic noise was measured in T1-PETRA in contrast to 34.8dB(A) in MPRAGE. The ICC scores of degree of myelination in all but one anatomical area for two readers indicated excellent agreement. T1-PETRA is very quiet and has good image quality by using about one minute more scan time, and it could be substituted for MPRAGE in order to provide gentler scans to pediatric patients.

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