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Abstract #1788

A retrospective multi-site, multi-manufacturer comparison of T1-weighted anatomical brain scans using tissue classification

Alain Pitiot 1 , Olivier Mougin 2 , Nikos Evangelou 3 , and Paul S Morgan 4

1 School of Psychology, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom, 2 Sir Peter Mansfield MR Centre, University of Nottingham, United Kingdom, 3 Division of Clinical Neurology, University of Nottingham, United Kingdom, 4 Medical Physics, University of Nottingham, United Kingdom

Great care is taken during the set-up of multi-site neuroimaging MR studies to ensure that data from different scanners across different sites can be combined appropriately. In practice there is a limit to how similar imaging protocols can be. Here we take a pragmatic, retrospective approach to investigate whether protocol variations results in a measureable effect on the anatomical brain images of a single subject scanned multiple times on MR scanners from 2 manufacturers installed at 3 sites. Very little differences were found, suggesting that standardising multi-site protocols may be less critical when combining data.

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