Abstract #1816
Functional MRI of the visual pathway in conscious, awake marmosets
Jennifer L Ciuchta 1 , ChiaChun Hung 1,2 , Cecil Chern-Chyi Yen 1 , Daniel Papoti 1 , David A Leopold 2 , and Afonso C Silva 1
1
CMU/LFMI/NINDS, National Institutes of
Health, Bethesda, MD, United States,
2
SCNI/LN/NIMH,
National Institutes of Health, Bethesda, MD, United
States
The common marmoset (Callithrix jacchus), a small New
World monkey with a highly developed visual cortex, is
an emerging model to study primate visual processing.
Robust BOLD signals in cortical and subcortical areas
are measured while the animals are awake, and actively
engaged in the visual stimuli. A custom-printed helmet
with embedded surface coils restricted each subjects
head movement totally non-invasively. Higher cortical
areas in the ventral stream responded more strongly to
structured stimuli compared to scrambled controls. Our
results demonstrate the promise of using awake behaving
marmosets as a model for studying primate vision using
fMRI.
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