Abstract #1906
Preliminary Multi-Modal Image Analysis in Epilepsy using Simultaneous PET/MR
Yu-Shin Ding 1,2 , Bangbin Chen 3 , Mariana Lazar 1 , Christopher Glielmi 4 , and Orrin Devinsky 5
1
Radiology, New York University School of
Medicine, New York, NY, United States,
2
Psychiatry,
New York University School of Medicine, New York, NY,
United States,
3
National
Taiwan University Hospital, Taiwan,
4
Siemens
Healthcare, New York, NY, United States,
5
Neurology,
New York University School of Medicine, NY, United
States
Surgery for treatment-resistant epilepsy can be
effective, but the decision to operate depends on a
careful assessment of the risk-benefit profile for each
patient. A combined PET/MR scanner with simultaneous
acquisition allows direct correlation of PET data with
MR-detected patterns of neural synchrony in the brain,
facilitating the identification of an optimal biomarker.
To demonstrate this feasibility, we initiated a
comparative study in controls and epilepsy patients
using FDG at 7 functionally connected networks. Our
results showed significant group difference in
metabolism at visual and attention networks, and that
ALFF at PCC significantly correlated with SUV at
attention network.
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