Meeting Banner
Abstract #1908

MRI diffusion histogram analysis in paediatric optic pathway tumours with and without neurofibromatosis

Daniel Rodriguez 1 , Nigel P Davies 2,3 , L Abernethy 4 , Chris A Clark 5,6 , Tim Jaspan 7 , D Hargrave 6 , L MacPherson 3 , Martin O Leach 8 , G S Payne 8 , B L Pizer 4 , Andrew C Peet 2,9 , T Arvanitis 9,10 , Richard Grundy 1,7 , and Dorothee P Auer 1,7

1 University of Nottingham, Nottingham, Nottinghamshire, United Kingdom, 2 University of Birmingham, Birmingham, United Kingdom, 3 University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, 4 Alder Hey Childrens NHS Foundation Trust, Liverpool, United Kingdom, 5 University College London, London, United Kingdom, 6 Great Ormond Street Hospital, London, United Kingdom, 7 Nottingham University Hospitals Trust, Nottingham, United Kingdom, 8 The Institute of Cancer Research and Royal Marsden Hospital, Sutton, United Kingdom, 9 Birmingham Childrens Hospital NHS Foundation Trust, Birmingham, United Kingdom, 10 University of Warwick, Coventry, United Kingdom

The relationship between ADC histogram-based metrics and neurofibromatosis type1 (NF1) in optic pathway gliomas (OPG) is investigated. Non-NF1 OPGs are known to carry a significantly poorer prognosis without any differences in conventional MR imaging markers. This study suggests that there are no differences in ADC-based metrics between NF1 groups either.

This abstract and the presentation materials are available to members only; a login is required.

Join Here