Abstract #1908
MRI diffusion histogram analysis in paediatric optic pathway tumours with and without neurofibromatosis
Daniel Rodriguez 1 , Nigel P Davies 2,3 , L Abernethy 4 , Chris A Clark 5,6 , Tim Jaspan 7 , D Hargrave 6 , L MacPherson 3 , Martin O Leach 8 , G S Payne 8 , B L Pizer 4 , Andrew C Peet 2,9 , T Arvanitis 9,10 , Richard Grundy 1,7 , and Dorothee P Auer 1,7
1
University of Nottingham, Nottingham,
Nottinghamshire, United Kingdom,
2
University
of Birmingham, Birmingham, United Kingdom,
3
University
Hospitals Birmingham NHS Foundation Trust, Birmingham,
United Kingdom,
4
Alder
Hey Childrens NHS Foundation Trust, Liverpool, United
Kingdom,
5
University
College London, London, United Kingdom,
6
Great
Ormond Street Hospital, London, United Kingdom,
7
Nottingham
University Hospitals Trust, Nottingham, United Kingdom,
8
The
Institute of Cancer Research and Royal Marsden Hospital,
Sutton, United Kingdom,
9
Birmingham
Childrens Hospital NHS Foundation Trust, Birmingham,
United Kingdom,
10
University
of Warwick, Coventry, United Kingdom
The relationship between ADC histogram-based metrics and
neurofibromatosis type1 (NF1) in optic pathway gliomas (OPG)
is investigated. Non-NF1 OPGs are known to carry a
significantly poorer prognosis without any differences
in conventional MR imaging markers. This study suggests
that there are no differences in ADC-based metrics
between NF1 groups either.
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