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Abstract #1932

Study of Cerebral Venous Density in Alzheimers Disease using Susceptibility Weighted Magnetic Resonance Imaging

Jeff Thompson 1,2 , Kevin Whittingstall 3 , Nicolas Vigneau-Roy 3,4 , Mohammed A. Warsi 5 , and Michael D. Noseworthy 1,2

1 Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada, 2 Imaging Research Centre, St. Joseph's Healthcare, Hamilton, Ontario, Canada, 3 Department of Diagnostic Radiology, Sherbrooke University, Sherbrooke, Quebec, Canada, 4 Molecular Imaging Centre, Sherbrooke University, Sherbrooke, Quebec, Canada, 5 Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Using Susceptibility Weighted Magnetic Resonance Imaging, a significant increase in venous density was found in subjects with Alzheimers Disease (AD). This study used 37 suspected AD subjects and 16 healthy age-matched controls. The venous density was found for the whole brain, as well as the grey matter and white matter. The subjects brains were registered to an AD atlas and statistical testing was performed showing the brain regions of greatest venous difference.

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