Abstract #1932
Study of Cerebral Venous Density in Alzheimers Disease using Susceptibility Weighted Magnetic Resonance Imaging
Jeff Thompson 1,2 , Kevin Whittingstall 3 , Nicolas Vigneau-Roy 3,4 , Mohammed A. Warsi 5 , and Michael D. Noseworthy 1,2
1
Electrical and Computer Engineering,
McMaster University, Hamilton, Ontario, Canada,
2
Imaging
Research Centre, St. Joseph's Healthcare, Hamilton,
Ontario, Canada,
3
Department of Diagnostic
Radiology, Sherbrooke University, Sherbrooke, Quebec,
Canada,
4
Molecular
Imaging Centre, Sherbrooke University, Sherbrooke,
Quebec, Canada,
5
Psychiatry and Behavioural
Neurosciences, McMaster University, Hamilton, Ontario,
Canada
Using Susceptibility Weighted Magnetic Resonance
Imaging, a significant increase in venous density was
found in subjects with Alzheimers Disease (AD). This
study used 37 suspected AD subjects and 16 healthy
age-matched controls. The venous density was found for
the whole brain, as well as the grey matter and white
matter. The subjects brains were registered to an AD
atlas and statistical testing was performed showing the
brain regions of greatest venous difference.
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