Abstract #1998
Cortical thickness correlates with symptoms in adolescents newly diagnosed with Obsessive-Compulsive Disorder
Oscar Gustafsson 1,2 , Maria Ljungberg 1,2 , Arvid Carlsson 3 , Maria L Carlsson 3 , Eva Forssell-Aronsson 1,2 , Tord Ivarsson 4 , Lars Jnsson 5 , Karin Melin 4 , and Gran Starck 1,2
1
Division of Medical Physics and Medical
Engineering, Sahlgrenska University Hospital, Gteborg,
Sweden,
2
Department
of Radiation Physics, Gteborg University, Gteborg,
Sweden,
3
Institute
of Neuroscience and Physiology, Gteborg University,
Gteborg, Sweden,
4
Department
of Child & Adolescent Psychiatry, Gteborg University,
Gteborg, Sweden,
5
Department
of Radiology, Sahlgrenska University Hospital, Gteborg,
Sweden
A morphometric analysis of treatment-nave adolescents
newly diagnosed with obsessive-compulsive disorder (OCD),
utilizing the image analysis software FreeSurfer, was
performed. Cortical thickness and volume of subcortical
structures was examined with a multivariate method
(scaled subprofile modeling) which produces patterns of
areas related to the disorder. Analysis of difference
between patients compared to healthy controls and
correlation to symptom severity, measured with the
Childrens Yale-Brown Obsessive-Compulsive Scale (CYBOCS),
were performed. A significant correlation between
cortical thickness and CYBOCS was found. Areas of major
effect in the corresponding pattern included the left
fusiform gyrus and the left parietal lobe.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
