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Abstract #2039

Depiction of vessel pathology in stroke imaging at 7.0T using non-contrast MPRAGE

Vince Istvan Madai 1,2 , Federico C von Samson-Himmelstjerna 1,3 , Florian Weiler 3 , Nora Sandow 4 , Matthias Gnther 3 , Peter Vajkoczy 4 , Thoralf Niendorf 5 , Jens Wuerfel 6,7 , and Jan Sobesky 1,2

1 Centre for Stroke Research Berlin (CSB), Charit Universittsmedizin Berlin, Berlin, Berlin, Germany, 2 Department of Neurology, Charit Universittsmedizin Berlin, Berlin, Berlin, Germany, 3 Fraunhofer-Mevis, Bremen, Germany, 4 Department of Neurosurgery, Charit Universittsmedizin Berlin, Berlin, Germany, 5 Berlin Ultrahighfield Facility (B.U.F.F.), Max Delbrck Centrum (MDC), Berlin, Germany, 6 Neurocure Clinical Research Centre, Charit Universittsmedizin Berlin, Berlin, Germany, 7 Department of Radiology, Universitt Gttingen, Gttingen, Germany

MPRAGE imaging at 7T allows for the generation of intracranial angiographies (MRA). This is promising as TOF at 7T is limited owing to SAR-constraints. To be of clinical value, however, 7T MPRAGE-MRA has to offer at least the diagnostic level of the highest current clinical standard, e.g. TOF-MRA at 3T. In the present work, we analyzed 16 patients with cerebrovascular disease (stroke and moya-moya-disease) at 3T and 7T. We could show that 7T MPRAGE offers a diagnostic quality comparable to 3T TOF. This is promising, as high-resolution anatomic and vascular imaging could be performed using a single sequence at 7T.

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