The Evolution of Short-Term Plasticity in the Rat Hippocampus

DTI is a valuable method in exploring structural plasticity. Studies found changes following short tasks of only hours, but the initial temporal and spatial progression of this process is unknown. In the current study we used the Morris water maze paradigm to explore the evolution of plasticity in the hippocampus of adult rats at different stages of the learning process. Rats were scanned following diverse number of trials in the maze. Results show that the extent of change the tissue undergoes during the learning process is dynamic. Additionally, circular order of the spatial progression of these changes was found.

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