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Abstract #2192

Semi-automated application for kidney motion correction and filtration analysis in MR renography

Florian Rousset 1,2 , Clment Vachet 1 , Christopher Conlin 3 , Marta Heilbrun 3 , Jeff L. Zhang 3 , Vivian S. Lee 3 , and Guido Gerig 1

1 Scientific Computing and Imaging Institute, Salt Lake City, Utah, United States, 2 CPE Lyon, Lyon, France, 3 Utah Center for Advanced Imaging Research, Salt Lake City, Utah, United States

The glomerular filtration rate (GFR) is a crucial measurement for tailoring drug regimens and monitoring patients with liver cirrhosis via renography. Dynamic MRI presents sought contrast changes but also breathing motion, which we correct via kidney detection. We have developed a novel software offering an integrated user-friendly tool to register dynamic kidney series, select regions of interest, visualize time-varying concentration, and calculate GFR values. With 98.69% success rate in correction for motion of image frames, our tool runs on different pltaforms and provides robust registration while significantly reducing processing time and giving accurate GFR values compared to an existing software.

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