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Abstract #2219

Can Magnetic Resonance Spectroscopy reflect the Aggressiveness of Endometrial cancer?

Jie Zhang 1 , Qingwei Liu 1 , Shifeng Cai 1 , Changzhong Li 2 , Xichao Sun 3 , and Caixia Fu 4

1 Radiology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China, 2 Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China, 3 Pathology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China, 4 Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, Guangdong, China

This study was to investigate whether the choline-containing compounds (Cho) obtained from three-dimension 1H MRS with 3T system is associated with the aggressiveness of endometrial cancer (ECa). Thirty-eight patients with ECa and 19 patients with benign lesions in endometria or in submucosa (BLs-ESm) were included in this study. The ratio of sum of Cho to sum of water (Cho/water) was the statistical unit. The Cho/water can differentiate ECa from BLs-ESm and differentiate type II from type I ECa, but cant differentiate different stages ECa, as well as different grades ECa. Cho/water increased with the increase of tumor stage and size.

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