Abstract #2332
Correction for the Oblique Focus in MR-Guided Focused Ultrasound for the Treatment of Essential Tremor
Yuexi Huang 1 , Alec Hughes 2 , Michael L. Schwartz 3 , Andres M. Lozano 4 , and Kullervo Hynynen 1,2
1
Sunnybrook Research Institute, Toronto, ON,
Canada,
2
Department
of Medical Biophysics, University of Toronto, Toronto,
ON, Canada,
3
Division
of Neurosurgery, Sunnybrook Health Sciences Centre,
Toronto, ON, Canada,
4
Division
of Neurosurgery, Toronto Western Hospital, Toronto, ON,
Canada
Magnetic resonance guided focused ultrasound has shown
promising results in the treatment of essential tremor.
MR-based targeting and temperature monitoring ensured
precise lesioning of the ventral intermediate nucleus
(VIM) in the thalamus. However, although the centres of
VIM were precisely targeted, oblique lesion volumes
angled to the main acoustic axes were observed in our
initial patients, with the two most severe ones close to
45 degrees in the coronal plane. In this study, we
investigated the reason for this oblique focus,
reproduced results in a skull phantom, and demonstrated
solutions for correcting the obliqueness using MR
thermometry.
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