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Abstract #2340

Near-field management during MR-HIFU ablation in highly perfused organs

Joost Wijlemans 1 , Martijn de Greef 2 , Gerald Schubert 3 , Maurice van den Bosch 1 , Chrit Moonen 2 , and Mario Ries 2

1 Dept. Radiology, UMC Utrecht, Utrecht, Netherlands, 2 Image Sciences Institute, UMC Utrecht, Utrecht, Netherlands, 3 Philips Healthcare, Vantaa, Finland

During MR-HIFU ablation, heat accumulation in near-field tissues (i.e. between transducer and target) can cause thermal damage to healthy tissues. In seven porcine liver ablation experiments we studied a strategy for managing this risk. Active external tissue cooling was used to reduce the risk of thermal damage, while T2 thermometry was used to monitor heat accumulation in near-field tissues. This method can be used to adjust the re-sonication intervals during the procedure, reducing the risk of thermal damage while optimizing ablation speed. Unlike modeling methods, this strategy is effective regardless of ultrasound beam geometry, near-field tissue composition, and perfusion variations.

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