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Abstract #2350

Methods for 3D treatment envelope evaluation in transcranial MRgFUS

Henrik Oden 1,2 , Nick Todd 1 , Josh de Bever 3 , Scott Almquist 3 , Allison Payne 1 , MarJanna Dahl 4 , Kurt Albertine 4 , Douglas Christensen 5,6 , and Dennis L Parker 1

1 Utah Center for Advanced Imaging Research, Department of Radiology, University of Utah, Salt Lake City, Utah, United States, 2 Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah, United States, 3 School of Computing, University of Utah, Salt Lake City, Utah, United States, 4 Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States, 5 Department of Bioengineering, University of Utah, Salt Lake City, Utah, United States, 6 Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, Utah, United States

Methods for 3D intracranial treatment envelope evaluations for magnetic resonance guided focused ultrasound applications are described. A 3D segmented echo planar imaging pulse sequence is used to acquire k-space data that is subsampled in the ky-phase encode direction with a reductions factor of R=4. The data is reconstructed with a temporally constrained reconstruction algorithm and temperature maps are created with the proton resonance frequency shift method. The 3D treatment envelope is evaluated in terms of relative near-field heating, and hydrophone scans are used to investigate amount of phase aberration and intensity loss due to US-focusing through the skull bone.

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