Fast Double-Echo EPI Pulse Sequence for Thermal Focal Spot Localization During MR-guided Regional Hyperthermia Treatment
Tetiana Dadakova 1 , Johanna Gellermann 2 , Otilia Voigt 2 , John Matt Pavlina 1 , and Michael Bock 1
Medical Physics, Department of Diagnostic
Radiology, University Medical Center Freiburg, Freiburg,
of Radiation Oncology, University Hospital Tbingen,
Regional hyperthermia is used as a supplementary therapy
during cancer treatment to improve chemotherapy and
radiotherapy effect. The temperature of the cancerous
and healthy tissue is typically monitored with
temperature probes inserted into catheters. MR
thermometry with the proton resonance frequency method
allows for a non-invasive temperature monitoring, and
often conventional gradient echo techniques (FLASH) are
used to measure the phase changes during heating. In
this work, a double echo segmented EPI sequence (DEPI)
for MR thermometry during hyperthermia was developed.
The higher acquisition speed of DEPI can be exploited to
localize unwanted thermal focal spots in the body of the
patient, which can make the hyperthermia procedure safer
and more reliable.
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