Whole-Heart Myocardial BOLD MRI with Adenosine Stress Using Fast Free-Breathing 3D T2 Mapping: A Validation Study in Canines

Myocardial BOLD MRI is an emerging non-contrast approach in the assessment of ischemic heart disease. Most commonly used myocardial BOLD MR approaches utilized weighted imaging (T2-weighted, T2*-weighted or bSSFP). In spite the benefits these techniques have provided to the advancement of myocardial BOLD imaging, several limitations continue to persist.. Recently, we developed a fast, free breathing 3D T2 mapping technique that utilizes 100% imaging efficiency, which allows for full coverage of the whole left ventricle within 5 minutes. In this study, we demonstrate the practical utility of the approach using a canine model subjected adenosine stress.

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