Abstract #2389
Nonrigid 3D+t Image Registration for Temporal Averaging in Multiphase Coronary MR Angiography
Serena Y Yeung 1 , Nii Okai Addy 1 , R Reeve Ingle 1 , Bob S Hu 1,2 , and Dwight G Nishimura 1
1
Electrical Engineering, Stanford University,
Stanford, CA, United States,
2
Palo
Alto Medical Foundation, Palo Alto, CA, United States
High-resolution coronary magnetic resonance angiography
(CMRA) enables finer depiction of coronary vessel
detail, but at the same time introduces the challenge of
compensating for a loss in SNR. In this work we
demonstrate the ability of nonrigid 3D+t image
registration to correct for interphase cardiac motion in
multiphase acquisitions, thus enabling SNR gain through
temporal averaging of the aligned images. 3D+t
registration has two major advantages over standard 3D
registration in this application: transformations are
temporally as well as spatially smooth, and registration
is performed globally without bias towards a
specifically chosen reference image.
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