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Abstract #2399

Spatial variability in cardiovascular magnetic resonance myocardial T2-mapping

Anirudh Mirakhur 1 , Yoko Mikami 2 , Khayam Khan 2 , Andrew Howarth 2 , and Naeem Merchant 1,2

1 Diagnostic Imaging, University of Calgary, Calgary, Alberta, Canada, 2 Stephenson Cardiovascular MR Centre, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada

Cardiovascular magnetic resonance (CMR) T2-mapping has potentialfor the detection and quantification of myocardial edema but the regional variability is unknown. The mean T2 relaxation time of normal myocardium has been reported around 52-55 milliseconds (ms), with most measurements performed in the mid-ventricle slice. Hence, we imaged healthy volunteers to assess for slice variability of myocardial T2 values. With the steady state free precession (SSFP)-based T2 mapping technique, normal global T2 values vary based on the slice selection. Therefore, the use of a single best normal global T2 value for the entire myocardium may not be accurate. Based on our data, the mid-ventricle is the most reliable slice for T2 quantification and also the most specific for detection of global edema.

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