Spatial variability in cardiovascular magnetic resonance myocardial T2-mapping
Anirudh Mirakhur 1 , Yoko Mikami 2 , Khayam Khan 2 , Andrew Howarth 2 , and Naeem Merchant 1,2
Diagnostic Imaging, University of Calgary,
Calgary, Alberta, Canada,
Cardiovascular MR Centre, Libin Cardiovascular Institute
of Alberta, University of Calgary, Calgary, Alberta,
Cardiovascular magnetic resonance (CMR) T2-mapping has
potentialfor the detection and quantification of
myocardial edema but the regional variability is
unknown. The mean T2 relaxation time of normal
myocardium has been reported around 52-55 milliseconds
(ms), with most measurements performed in the
mid-ventricle slice. Hence, we imaged healthy volunteers
to assess for slice variability of myocardial T2 values.
With the steady state free precession (SSFP)-based T2
mapping technique, normal global T2 values vary based on
the slice selection. Therefore, the use of a single best
normal global T2 value for the entire myocardium may not
be accurate. Based on our data, the mid-ventricle is the
most reliable slice for T2 quantification and also the
most specific for detection of global edema.
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