Abstract #2423
Waveguide Magnetic Resonance Elastography of the Left Ventricle in a Pressure Varying Model
Ria Mazumder 1 , Bradley D. Clymer 1 , Richard D. White 2 , Anthony J. Romano 3 , and Arunark Kolipaka 2
1
Department of Electrical and Computer
Engineering, The Ohio State University, Columbus, OH,
United States,
2
Department
of Radiology, The Ohio State University, Columbus, OH,
United States,
3
Department
of The Navy, Naval Research Laboratory, Washington, DC,
United States
Myocardial stiffness (MS) is elevated in heart failure
with preserved ejection fraction (HFPEF) wherein the
ejection fraction (EF) of the left ventricle (LV) stays
normal. Hence, current diagnostic tools that measure EF
of the LV inhibit diagnosis of HFPEF. Therefore, there
is a need to develop a clinical tool to estimate
myocardial stiffness in order to characterize the
pathophysiological conditions associated with the
disease. In this study, we measure myocardial stiffness
in a porcine model with varying LV pressure, using
waveguide magnetic resonance elastography to estimate
anisotropic stiffness of the LV myocardium.
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