Abstract #2431
Accuracy, Precision, and Reproducibility Comparison of T 1 Mapping Sequences
Sbastien Roujol 1 , Sebastian Weingrtner 1,2 , Murilo Foppa 1 , Kelvin Chow 3 , Keigo Kawaji 1 , Kraig V Kissinger 1 , Beth Goddu 1 , Sophie Berg 1 , Peter kellman 4 , Warren J. Manning 1,5 , Richard B. Thompson 3 , and Reza Nezafat 1
1
Department of Medicine, Beth Israel
Deaconess Medical Center / Harvard Medical School,
Boston, MA, United States,
2
Computer
Assisted Clinical Medicine, University Medical Center
Mannheim, Heidelberg University, Mannheim, Germany,
3
Department
of Biomedical Engineering, Faculty of Medicine and
Dentistry, University of Alberta, Edmonton, Alberta,
Canada,
4
National
Heart, Lung, and Blood Institute, National Institutes of
Health, Bethesda, MD, United States,
5
Department
of Radiology, Beth Israel Deaconess Medical Center /
Harvard Medical School, Boston, MA, United States
Quantitative myocardial T
1
mapping
provides in-vivo tissue characterization for assessment
of cardiomyopathies. The extracellular volume fraction (ECV)
can be calculated from pre and post-contrast T
1
maps
and shows promise for the detection of diffuse
myocardial fibrosis. Several techniques have been
recently proposed for myocardial T
1
mapping.
However, no comprehensive comparison has been performed
across these methods. In this study, we sought to
analyze T
1
and
ECV measurements in term of accuracy, precision and
reproducibility from four T1 mapping techniques:
Modified Look-Locker Inversion Recovery (MOLLI),
Shortened MOLLI (ShMOLLI), Saturation recovery
single-shot acquisition (SASHA), and SAturation Pulse
Prepared Heart rate independent Inversion-REcovery
sequence (SAPPHIRE).
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