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Abstract #2449

Pilot Data on Inter-Centre and Inter-Vendor Comparison of MOLLI and ShMOLLI T1 Mapping Variants at 3T

David A Broadbent 1,2 , David M Higgins 3 , Vanessa Ferreira 4 , Alexander Liu 4 , Claudia Marini 4 , Christopher M Kramer 5 , Sven Plein 1 , Stefan Neubauer 4,6 , and Stefan K Piechnik 4

1 Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, United Kingdom, 2 Division of Medical Physics, University of Leeds, Leeds, United Kingdom, 3 Philips Healthcare, Guildford, United Kingdom, 4 Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom, 5 Department of Medicine and Radiology, University of Virginia Health System, Charlottesville, Virginia, United States, 6 Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom

In this study we performed an inter-site, inter-vendor comparison of myocardial T1 mapping in preparation for a large multi-centre study. Native myocardial T1 measurements were compared in five healthy volunteers using different MOLLI variants on two 3T scanners (one Siemens, one Philips) from different vendors at different UK centres. Some bias (~2%) was observed between one variant and the other two, although this variant was only tested at one site and requires further validation. Bias between the other variants and the vendors/sites was small, providing support for the use of these techniques in multi-centre studies.

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