Abstract #2461
Dynamic changes of myocardial salvage index after reperfusion: A rat study at 7T
Rui Xia 1 , Xi Lu 1 , Bing Zhang 1 , Yuqing Wang 1 , Jie Zheng 2 , and Fabao Gao 1
1
Department of radiology, West China
Hospital, Sichuan University, Chengdu, Sichuan, China,
2
Mallinckrodt
Institute of Radiology, Washington University School of
Medicine in St. Louis, Missouri, United States
In this study, six rats with 30min myocardial ischemia
followed by different reperfusion time (3h, 6h, 12h,
24h) were investigated. And the simplified T2-mapping
method was implemented at a 7.0T MRI system. We found
that the edema size decreased from 3h to 6h, and kept
the same between 6h and 24h. Myocardial salvage index
increased while infarction size decreased from 6h to
24h. So the longer reperfused time will increase
myocardial salvage index between 6h and 24h in the acute
myocardial ischemia. In conclusion, reperfusion may be a
useful treatment for the early phase of acute myocardial
ischemia.
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