Abstract #2477
Assessment of Aortic Stenosis Severity using Bayesian Multipoint Phase-Contrast MRI
Christian Binter 1 , Alexander Gotschy 1,2 , Robert Manka 1,2 , Simon H. Sndermann 3 , and Sebastian Kozerke 1,4
1
Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland,
2
Dept.
of Cardiology, University Hospital Zurich, Zurich,
Switzerland,
3
Division
of Cardiovascular Surgery, University Hospital Zurich,
Zurich, Switzerland,
4
Imaging
Sciences and Biomedical Engineering, King's College
London, London, United Kingdom
The classification of aortic stenosis severity using
Doppler sonography is based on the velocities across the
valve and does not necessarily reflect the additional
workload of the heart. Phase-Contrast MRI offers the
possibility of quantifying the energy dissipated in
turbulent flow and thereby potentially providing an
objective measure of disease severity. Results from 16
patients and 10 age-matched controls are presented and
compared to conventional diagnostic parameters
determined by Doppler sonography. To analyze robustness,
inter- and intra-observer variability analysis is
performed.
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