Abstract #2494
Quantitative assessment of spatial and temporal pulmonary arterial regurgitation after repaired Tetralogy of Fallot
Pei-Hsin Wu 1 , Hsiao-Wen Chung 1 , Cheng-Wen Ko 2 , and Ming-Ting Wu 3
1
Institute of Biomedical Electronics and
Bioinformatics, National Taiwan University, Taipei,
Taiwan,
2
Department
of Computer Science and Engineering, National Sun
Yat-Sen University, Kaohsiung, Taiwan,
3
Department
of Radiology, Kaohsiung Veterans General Hospital,
Kaohsiung, Taiwan
Pulmonary regurgitation is commonly observed in patients
after repaired tetralogy of Fallot. The regurgitation
fraction measured via PC-MRI to evaluate the need for
pulmonary valve replacement, however, does not contain
spatial flow inhomogeneity information. Since forward
and regurgitant flow could occur in the pulmonary
arteries and be recorded simultaneously in any single
cardiac phase, we propose a newly defined parameter
which explores both the spatial and temporal existence
of blood flow regurgitation by pixelwise analysis of
flow velocity. Preliminary result on main pulmonary
arteries from ten patients suggests potential assistance
value in the understanding of pathophysiology in
tetralogy of Fallot.
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