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Abstract #2502

Blood flow velocity and pulsatility analysis of cerebral small perforating arteries with 7 Tesla quantitative flow MRI.

Willem Bouvy 1 , Geert Jan Biessels 2 , Jaap Kappelle 2 , Peter R Luijten 3 , and Jaco Zwanenburg 3

1 Brain Center Rudolf Magnus, Department of Neurology, Utrecht University Medical Centre, Utrecht, Utrecht, Netherlands, 2 Brain Center Rudolf Magnus, Department of Neurology, Utrecht University Medical Centre, Utrecht, Netherlands, 3 Department of Radiology, Utrecht University Medical Centre, Utrecht, Netherlands

Aim: To measure blood flow velocity and pulsatility in small perforating arteries in the cerebral white matter with 7 Tesla Qflow MRI. Method: Six volunteers aged 18-30 were scanned, and twelve perforating arteries were analyzed. Results: Flow was pulsatile in all arteries, with a mean velocity of 0.9cm/s (range 0.23-2.01), and mean pulsatility index of 0.51(range 0.29-0.83). Conclusion: Velocity pulsations in small arteries in the white matter can be directly measured in humans with 7 Tesla Qflow MRI. Partial volume effects and the direction of flow measurement may have affected our results, and further validation of this method is needed.

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