Abstract #2502
Blood flow velocity and pulsatility analysis of cerebral small perforating arteries with 7 Tesla quantitative flow MRI.
Willem Bouvy 1 , Geert Jan Biessels 2 , Jaap Kappelle 2 , Peter R Luijten 3 , and Jaco Zwanenburg 3
1
Brain Center Rudolf Magnus, Department of
Neurology, Utrecht University Medical Centre, Utrecht,
Utrecht, Netherlands,
2
Brain
Center Rudolf Magnus, Department of Neurology, Utrecht
University Medical Centre, Utrecht, Netherlands,
3
Department
of Radiology, Utrecht University Medical Centre,
Utrecht, Netherlands
Aim: To measure blood flow velocity and pulsatility in
small perforating arteries in the cerebral white matter
with 7 Tesla Qflow MRI. Method: Six volunteers aged
18-30 were scanned, and twelve perforating arteries were
analyzed. Results: Flow was pulsatile in all arteries,
with a mean velocity of 0.9cm/s (range 0.23-2.01), and
mean pulsatility index of 0.51(range 0.29-0.83).
Conclusion: Velocity pulsations in small arteries in the
white matter can be directly measured in humans with 7
Tesla Qflow MRI. Partial volume effects and the
direction of flow measurement may have affected our
results, and further validation of this method is
needed.
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