Validation of a Cardiovascular MRI Protocol for Combined Assessment of Contrast-Enhanced Whole Body Angiography and Cardiac Function within a Single Examination
Stephen J Gandy 1 , Jill Belch 2 , Ian Cavin 1 , Elena Crowe 3 , Jennifer Macfarlane 1 , Patricia Martin 3 , Shona Matthew 2 , Matthew Lambert 2 , R Stephen Nicholas 1 , Allan Struthers 2 , Shelley Waugh 1 , Jonathan Weir-McCall 2 , Richard White 3 , and J Graeme Houston 2
NHS Tayside Medical Physics, Ninewells
Hospital, Dundee, Angus, United Kingdom,
of Medicine, University of Dundee, Dundee, Angus, United
Tayside Clinical Radiology, Ninewells Hospital, Dundee,
Angus, United Kingdom
The aim of this study was to test a novel cardiovascular
MRI protocol capable of acquiring cardiac MR (CMR) data
(including myocardial delayed enhancement) and
whole-body MRA (WB-MRA) data within a single
examination. The protocol was divided into five phases,
consisting of (i) localisers, (ii) CINE MR of left
ventricular function, (iii) WB-MRA part 1, (iv)
myocardial delayed enhancement, and (v) WB-MRA part II.
CMR segmentation and WB-MRA scoring evaluation was
undertaken by two teams of multiple observers, and good
repeatability was established. The protocol was well
tolerated by volunteers and therefore deemed suitable
for larger population-based studies.
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