Non-contrast-enhanced MR angiography of the thoracic central veins

Imaging of the thoracic central veins is important for patients with central venous obstruction or with restricted venous access, where contrast-agent administration is difficult. We have developed a subtraction-based non-contrast-enhanced MR angiography method for central vein imaging, using a balanced SSFP readout with dual iMSDE flow-suppression, respiratory navigator gating, spatial saturation, and dual-inversion recovery for fat suppression. Comparisons in six healthy volunteers scored this approach more highly in terms of image quality, artifacts and background suppression, in comparison with alternative versions using spectral fat suppression or no fat suppression, and with breath-hold techniques.

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