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Abstract #2522

3D coronary dark-blood interleaved with gray-blood (cDIG) MRI

Guoxi Xie 1,2 , Bin Sun 3 , Qingyi Dai 4 , Antonio Hernandez Conte 2 , Xiaoming Bi 5 , Yutaka Natsuaki 5 , Jing An 6 , Reza Arsanjani 2 , Xin Liu 1 , Hairong Zheng 1 , Zhanming Fan 4 , Daniel Berman 2 , Debiao Li 2 , and Zhaoyang Fan 2

1 Shenzhen Key Lab for MRI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China, 2 Cedars Sinai Medical Center, Los Angeles, CA, United States, 3 Union Hospital, Fujian Medical University, Fujian, China, 4 Radiology Department, Anzhen Hospital, Beijing, China, 5 Siemens Healthcare, Los Angeles, CA, United States, 6 MR Collaborations NE Asia, Siemens Healthcare, Beijing, China

3D dark-blood MRI techniques have shown great potential in coronary plaque burden assessment. However, substantial variability in quantification could result from superficial calcification that often mimics part of lumen because of its low signal. Recent work shows that gray-blood contrast can help separate superficial calcification from lumen. Thus, the purpose of this work was to develop a 3D coronary dark-blood interleaved with gray-blood (cDIG) MRI technique to improve the visualization and quantification of coronary plaque. In vivo experiment results demonstrated that dual contrasts were simultaneously acquired using the proposed method without compromising dark-blood contrast and scan time.

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