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Abstract #2524

Black-blood vessel wall imaging using SLR designed velocity selective RF pulse

Yunduo Li 1 , Lirong Yan 2 , Mayank Jog 2 , Robert Smith 2 , Karen Ying 3 , Rui Li 4 , Chun Yuan 4 , and Danny JJ Wang 2

1 Department of Biomedical Engineering, Tsinghua University, Beijing, Beijing, China, 2 Neurology, UCLA, CA, United States, 3 Department of Engineering Physics, Tsinghua University, Beijing, China, 4 Center for Biomedical Imaging Research, Tsinghua University, Beijing, China

A novel method which employs the velocity-selective RF pulse to suppress the signal from flowing blood is presented and a design example is shown. Simulation results demonstrate that the velocity-selective profile of the designed pulse meets the demand of vessel wall imaging. Phantom and in-vivo studies verified the designed pulse can invert flowing spins of high velocity and leave the static spins undisturbed. All results imply that the pulse is potentially suitable for blood suppression in vessel wall imaging. The method enables the pulse designer to trade off among important parameters such as pulse duration, cut-off velocity and pass-band ripples.

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