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Abstract #2534

High-resolution multi-parametric characterization of atherosclerotic lesions with 3T intravascular MRI

Guan Wang 1,2 , M. Arcan Erturk 1,2 , Shashank Sathyanarayana Hegde 2 , and Paul A. Bottomley 1,2

1 Electrical & Computer Engineering, Johns Hopkins University, Baltimore, MD, United States, 2 Russell H. Morgan Dept. of Radiology & Radiological Sciences, Johns Hopkins University, Baltimore, MD, United States

The ability to characterize atheroma components is central to assessing the status of vessel disease, and its progression and response to intervention. High-field intravascular MRI (IVMRI) offers the potential for assessing T 1 , T 2 , proton density and lipid burden in healthy and diseased vessels at a resolution approaching 100m. Here, results from multi-parametric, 200m-resolution intravascular IVMRI employing a novel Tri-Flip-Angle method are presented. T 1 , T 2 and proton density are mapped with B 1 -self-correction in only four acquisitions, while the lipid pool is imaged by Dixon (or selective saturation) techniques in human iliac artery specimens.

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