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Abstract #2536

Fast 3D isotropic high spatial resolution MRI of peripheral vessel wall at 3T

Guoxi Xie 1,2 , Xiaoming Bi 3 , Jing An 4 , Xin Liu 1 , Hairong Zheng 1 , Debiao Li 2 , and Zhaoyang Fan 2

1 Shenzhen Key Lab for MRI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China, 2 Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, 3 Siemens Healthcare, Los Angeles, CA, United States, 4 MR Collaborations NE Asia, Siemens Healthcare, Beijing, China

Peripheral artery disease (PAD) is a slow and progressive circulation disorder which not only causes pain and disability. Flow independent dark-blood 3D MRI is suitable for peripheral artery vessel wall imaging with large coverage. Previous studies have proposed SPACE and MERGE for 3D peripheral artery vessel wall imaging. However, SPACE still needs long scan time while MERGE is sensitive to B0 inhomogeneous. In this work, a 3D DANTE-Prep dark-blood GRE sequence was developed for peripheral artery vessel wall imaging. It allows screening bilateral 30-cm-long peripheral arteries within 4 minutes with isotropic high spatial resolution (0.720.720.72 mm3).

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