Single-shot and Readout Segmented EPI: Geometric Fidelity of 3T Prostate DWI

We compare image quality and distortion in the prostate diffusion-weighted MRI using single-shot EPI (SS-DWI) and multi-shot readout segmented EPI (MS-DWI) in clinical patients (N=12) undergoing in-bore MRI-guided prostate biopsy. The use of MS-DWI led to marked reduction of distortion under conditions that resulted in non-diagnostic SS-DWI images, with moderate increase in scan time (2 vs 3:30 min). Image quality and distortion severity were strongly correlated with the presence of air for SS-DWI, but not for MS-DWI. Distortion reduction agreed with the theoretically expected values. MS-DWI is thus preferable for improved accuracy of prostate target localization and interventional applications.

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