The comparison of diffusion and perfusion characteristics among the different types of uterine fibroids based on T2WIs: an intravoxel incoherent motion MRI study

The prognoses of non-invasive therapies such as magnetic resonance-guided focused ultrasound surgery (MRgFUS) and GnRH analogue of uterine leiomyomas were proved have a relationship with the signal intensity of tumor on T2WI. However the reason is not definite yet. We performed Intravoxel incoherent motion (IVIM) MR study on a cohort of patients to compare the diffusion and perfusion characteristics of uterine fibroid with different T2WI type. The results indicated that the cellularity is tighter in Type 1 and looser in Type 3 among 3 fibroid types, whereas perfusion parameters of Intravoxel incoherent motion (IVIM), seem no differences among them. Thus, the present results implied that IVIM technique facilitated the understanding of the tissue characteristics in uterine fibroid and proposed to guide patient selection for MRgFUS ablation.

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