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Abstract #2608

Validation of mean apparent propagator MRI

Alan Seth Barnett 1,2 , Elizabeth Hutchinson 1,2 , Ferenc Horkay 1 , Michal Komlosh 1,2 , Evren Ozarslan 3 , Carlo Pierpaoli 1 , and Peter Basser 1

1 NICHD, NIH, Bethesda, MD, United States, 2 CNRM, USUHS, Bethesda, MD, United States, 3 Department of Radiology, Harvard Medical School, Boston, MA, United States

Mean apparent propagtor MRI (MAP-MRI) is a method of using diffusion MRI to map tissue microstructure. To evaluate the accuracy and precision of MAP-MRI we use a test system consisting of an array of microscopic cylinders. We use both simulated data, computed using the multiple correlation function (mcf) method, and real diffusion imaging data of a special phantom. We report the accuracy and precision of several MAP parameters as a function of the signal-to-noise ratio of the non-diffusion weighted images.

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