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Abstract #2612

Interpretation of diffusion MRI data using a gamma distribution model

Koichi Oshio 1 , Hiroshi Shinmoto 2 , and Robert Mulkern 3

1 Department of Diagnostic Radiology, Keio University, Shinjuku-ku, Tokyo, Japan, 2 Department of Radiology, National Defence Medical College, Tokorozawa, Saitama, Japan, 3 Department of Radiology, Children's Hospital, Boston, MA, United States

Although many models have been proposed to interpret non-Gaussian diffusion MRI data in biological tissues, it is often difficult to see the correlation between the MRI data and the histological changes in the tissue. In this work, a statistical model based on the gamma distribution is proposed. Using this model, the diffusion MR data is well fitted, and histological interpretation of the data is possible.

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