Two-Voxel Spectroscopy With Dynamic B0 Shimming and Flip Angles at Ultra High Field
Clark Lemke 1 , Aaron Hess 2 , Velicia Bachtiar 1 , Stuart Clare 1 , Charlotte Stagg 1 , Peter Jezzard 1 , and Uzay Emir 1
FMRIB, University of Oxford, Oxford,
Oxfordshire, United Kingdom,
University of Oxford, Oxford, Oxfordshire, United
Dynamic B0 shimming enables rapid switching between
different B0 shim solutions for multiple locations to
better optimize spectroscopy sequence performance. This
can further be improved by dynamically applying
different flip angles for each location. This technique
is employed to acquire metabolite concentrations from 2
voxels located in the motor cortex of each hemisphere in
an interleaving fashion. This procedure is presented
alongside single voxel measurements and the
neurochemical profiles from 3 subjects are presented.
Results suggest that dynamic B0 shimming and flip angles
allow for accurate measurement of 14 metabolites in
multiple locations in one spectroscopy session.
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