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Abstract #2899

Two-Voxel Spectroscopy With Dynamic B0 Shimming and Flip Angles at Ultra High Field

Clark Lemke 1 , Aaron Hess 2 , Velicia Bachtiar 1 , Stuart Clare 1 , Charlotte Stagg 1 , Peter Jezzard 1 , and Uzay Emir 1

1 FMRIB, University of Oxford, Oxford, Oxfordshire, United Kingdom, 2 OCMR, University of Oxford, Oxford, Oxfordshire, United Kingdom

Dynamic B0 shimming enables rapid switching between different B0 shim solutions for multiple locations to better optimize spectroscopy sequence performance. This can further be improved by dynamically applying different flip angles for each location. This technique is employed to acquire metabolite concentrations from 2 voxels located in the motor cortex of each hemisphere in an interleaving fashion. This procedure is presented alongside single voxel measurements and the neurochemical profiles from 3 subjects are presented. Results suggest that dynamic B0 shimming and flip angles allow for accurate measurement of 14 metabolites in multiple locations in one spectroscopy session.

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