Abstract #2901
Comparison of a short-TE whole brain MR spectroscopic imaging to single voxel spectroscopy for measurement of metabolite concentrations in human brain
Xiao-Qi Ding 1 , Andrew A. Maudsley 2 , Mohammad Sabati 2 , Sulaiman Sheriff 2 , and Heinrich Lanfermann 1
1
Institute of Diagnostic and Interventional
Neuroradiology, Hannover Medical School, Hannover, Lower
Saxony, Germany,
2
Department
of Radiology, University of Miami School of Medicine,
FL, United States
A short TE whole brain MR spectroscopic imaging (wbMRSI)
for detection of focal metabolite concentrations in
human brain within a clinically acceptable scan time has
been evaluated. Twenty healthy volunteers were scanned
both with wbMRSI and Single-Voxel Spectroscopy (SVS),
and the measurements compared. The results showed that
short TE wbMRSI could be used to estimate focal
concentrations of NAA, Cho, tCr, mI, and Glx as well as
those with SVS, with additional advantages that
metabolite concentrations could be evaluated at more
brain regions.
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