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Abstract #2916

Sensitivity Encoding for Fast MR Spectroscopic Imaging Water Reference Acquisition

Rebecca Birch 1,2 , Andrew C. Peet 2,3 , Theodoros N. Arvanitis 2,4 , and Martin Wilson 2,3

1 PSIBS Doctoral Training Centre, University of Birmingham, Birmingham, United Kingdom, 2 Department of Oncology, Birmingham Childrens Hospital NHS Foundation Trust, Birmingham, United Kingdom, 3 School of Cancer Sciences, University of Birmingham, United Kingdom, 4 Institute of Digital Healthcare, WMG, University of Warwick, Coventry, United Kingdom

Water reference scans for Magnetic Resonance Spectroscopic imaging (MRSI) provide absolute quantification of metabolites; long acquisition times mean it is not used routinely in clinic. Sensitivity encoding (SENSE) is a parallel imaging technique which can reduce scan time. SENSE and its reconstruction of water reference data is compared with a default reduced resolution technique. 2D MRSI water reference data were collected for a phantom and three volunteers at 3T. Water amplitude and line width maps were created and variance with the full acquisition assessed. SENSE was found to be more successful, validating its use for routine water reference data collection.

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