In-vivo 37 Cl Magnetic Resonance Imaging at 7 Tesla

With a customer made solenoid coil ³⁷ Cl imaging at a 7T whole- body MRI system at a frequency of 24.3 MHz was performed although the natural abundance of ³⁷ Cl is lower than that of the for measurements preferred ³⁵ Cl. For phantoms with 0.9% sodium chloride solution and different agar concentrations the relaxation times (T2 ^* and T1) were determined and compared to the relaxation times of ³⁵ Cl. The relaxation times are longer than the ones of ³⁵ Cl. In-vivo imaging of a narcotized rat showed the feasibility of MRI using the ³⁷ Cl isotope in comparison with ³⁵ Cl and showed high signal intensities.

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