Abstract #2986
Variable Flip Angle 3D-GRASE for Increased Spatial Coverage and Improved Point Spread Function in High Resolution fMRI at 7T
Valentin G. Kemper 1 , Federico De Martino 1 , An T. Vu 2 , David A. Feinberg 3 , Essa Yacoub 2 , and Rainer Goebel 1
1
Department of Cognitive Neuroscience,
Maastricht University, Maastricht, Limburg, Netherlands,
2
Radiology,
Center for Magnetic Resonance Research, University of
Minnesota, Minneapolis, Minnesota, United States,
3
Helen
Wills Institute of Neuroscience, University of
California, Berkeley, United States
Variable flip angle (VFA) refocusing schemes for
Inner-Volume 3D-GRASE were designed to improve spatial
coverage and point-spread along the partition direction
in high-resolution functional MRI at 7T. Phase graph
theory was used to calculate signal contributions from
spin-echoes and stimulated echoes along the echo train.
The simulations yield point-spread functions, which are
in good agreement with such estimated from non-phase
encoded acquisitions. In a simple visual activation
experiment, almost twice the number of slices were
acquired per echo train while maintaining the temporal
signal to noise ratio, functional sensitivity, and
point-spread properties of a reference acquisition with
conventional 180 refocusing.
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