Abstract #2990
Employing Wideband Gradient-Echo MRI to Map the Functional Activation in Rat Somatosensory Cortex with Enhanced Spatial Resolution
Yun-An Huang 1,2 , Shih-Hsien Yang 3 , Tzu-Hao Harry Chao 4 , Edzer L. Wu 5 , Der-Yow Chen 6 , Kuan-Hung Cho 7 , Yeun-Chung Chang 8 , Changwei W. Wu 3 , Li-Wei Kuo 9 , and Jyh-Horng Chen 1,2
1
Department of Electrical Engineering,
National Taiwan University, Taipei, Taipei, Taiwan,
2
Neurobiology
and Cognitive Science Center, National Taiwan
University, Taipei, Taipei, Taiwan,
3
Graduate
Institute of Biomedical Engineering, National Central
University, Taoyuan, Taiwan,
4
Department
of Life Science, National Taiwan University, Taipei,
Taiwan,
5
Institute
of Biomedical Engineering, National Taiwan University,
Taipei, Taiwan,
6
Department
of Psychology, National Cheng Kung University, Tainan,
Taiwan,
7
Institute
of Brain Science, National Yang Ming University, Taipei,
Taiwan,
8
College
of Medicine, National Taiwan University, Taipei, Taiwan,
9
Institute
of Biomedical Engineering and Nanomedicine, National
Health Research Institutes, Miaoli County, Taiwan
Functional MRI (fMRI) has been widely used to discover
the brain functions by examining the T2* weighted
blood-oxygen-level-dependent (BOLD) signals. However,
higher spatial or temporal resolution is urgently needed
for investigating the hemodynamic responses from subtle
neural activities. In this study, single carrier
Wideband MRI with 2-fold acceleration was employing on
the conventional gradient echo sequence (WB-GRE) in rat
fMRI experiments with electrical stimulation to
forepaws. Our preliminary results show WB-GRE could
provide higher spatial or temporal resolution. Also, the
capability of using Wideband technology on fMRI to map
the functional activation with enhanced spatial
resolution has been demonstrated.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
