Abstract #3018
Self-regulation of rACC activation in patients with Postherpetic Neuralgia:A preliminary study using Real-time fMRI neurofeedback
Lijia Ma 1 , Min Guan 1 , Liang Li 2 , Li Tong 2 , Yong Zhang 3 , Dandan Zheng 3 , Bin Yan 2 , Meiyun Wang 1 , and Dapeng Shi 1
1
Radiology, People's Hospital of Zhengzhou
University, ZhengZhou, HeNan, China,
2
National
digital swiching system engineering and technological
research center, HeNan, China,
3
GE
Healthcare, Beijing, China
Previous studies found that by using real-time
functional MRI (rtfMRI) neurofeedback, subjects could
learn to control activation in the target brain
region.We hypothesize that through rtfMRI
neurofeedback,PHN patients could learn to control the
activation in rACC,a region involved in pain perception
and regulation.5 PHN patients performed a corresponding
imagery task and were instructed to increase and
decrease activation in rACC using rtfMRI
neurofeedback.3/5 patients learned to change their fMRI
signal with intermittent feedback training.Also there
was a corresponding change in the perception of
pain.This investigation may provide an alternative way
for treatment of severe, chronic clinical pain in the
future.
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