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Abstract #3086

Modular organization of mouse brain functional connectivity

Carlo Nicolini 1 , Adam Liska 1 , Francesco Sforazzini 1 , Alberto Galbusera 1 , Angelo Bifone 1 , and Alessandro Gozzi 1

1 MRI Laboratory, Istituto Italiano di Tecnologia, Centre for Neuroscience and Cognitive Sciences, Rovereto, Trento, Italy

We recently described the presence of distributed intrinsic connectivity networks in the mouse brain homologous to those observed in primates and humans. Here we used complex network analysis to describe the functional topology of the resting mouse brain. We found that the mouse brain can be segregated into four stable and anatomically plausible communities that can be associated to known distributed brain functions and related to known connectional partitions of the human brain. These initial results suggest that the mouse brain conserves fundamental topological properties that are also seen in higher species.

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