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Abstract #3171

Quantitative Susceptibility Mapping: High Resolution Imaging of the Dentate Nucleus at High Field Strength (7T)

PINAR SENAY ZBAY 1,2 , Michael Wyss 2 , Cristina Rossi 1 , Klaas Paul Prssmann 2 , and Daniel Nanz 1

1 University Hospital Zrich, Institute for Diagnostic and Interventional Radiology, Zrich, Zrich, Switzerland, 2 Institute for Biomedical Engineering, University and ETH Zrich, Zrich, Zrich, Switzerland

In-vivo imaging of deep cerebellar structures and deep nuclei is difficult even by MRI due to their small size and limited contrast. In this work we aimed at a visualization and characterization of the fine corrugated band that represents the dentate nucleus (DN) by means of high-resolution Quantitative Susceptibility Mapping (QSM) at 7T. QSM depicted the DN band with significantly better contrast than T2*-weighted images or T2* maps. Quantitative susceptibility differences of the right and left DN band with respect to frontal white matter could be measured. QSM-based estimates of right and left DN band volumes are also reported.

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